Tris-EDTA (TE) Buffer is a standard buffer solution widely utilized in molecular biology applications, particularly those involving DNA and RNA handling. This formulation contains a 20X concentration of Tris, which provides effective buffering capacity, and EDTA, which helps protect nucleic acids from degradation by binding magnesium and other divalent metal ions. The buffer supports stable pH control within the range of 7.5 to 8.5 and is commonly used for DNA and RNA gel electrophoresis as well as automated DNA sequencing workflows.