Considerations and Limitations of Osmolality Testing | |
|---|---|
Dilute concentrated samples | High concentrations of salts, detergents, sugars, and glycerol may require a 10X sample dilution from a 1X dilution before accurate osmolality determination. |
Ensure sample is uniform | Sample bubbles or incorrect volumes may cause output errors, along with solutions that aren't uniform upon formulation. This will affect the freezing temperatures in which the solutions will be analyzed and may cause errors in on the osmolality meter. |
Ensure proper sample preparation | Proper sample preparation and handling is essential for reliable results in osmolality testing. Any risks of contamination during the samples formulation, or errors in component makeup may result in the incorrect osmolality reading. |